Crystal engineering of exemestane to obtain a co-crystal with enhanced urease inhibition activity

Co-crystallization is a phenomenon widely employed to enhance the physio-chemical and biological properties of active pharmaceutical ingredients (APIs). Exemestane, or 6-methyl­ideneandrosta-1,4-diene-3,17-dione, is an anabolic steroid used as an irreversible steroidal aromatase inhibitor, which is...

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Detalles Bibliográficos
Autores principales: Fatima, Syeda Saima, Kumar, Rajesh, Choudhary, M. Iqbal, Yousuf, Sammer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949591/
https://www.ncbi.nlm.nih.gov/pubmed/31949910
http://dx.doi.org/10.1107/S2052252519016142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949591/
https://www.ncbi.nlm.nih.gov/pubmed/31949910
http://dx.doi.org/10.1107/S2052252519016142

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