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Crystal engineering of exemestane to obtain a co-crystal with enhanced urease inhibition activity

Co-crystallization is a phenomenon widely employed to enhance the physio-chemical and biological properties of active pharmaceutical ingredients (APIs). Exemestane, or 6-methylideneandrosta-1,4-diene-3,17-dione, is an anabolic steroid used as an irreversible steroidal aromatase inhibitor, which is...

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Detalles Bibliográficos
Autores principales:	Fatima, Syeda Saima, Kumar, Rajesh, Choudhary, M. Iqbal, Yousuf, Sammer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2020
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949591/ https://www.ncbi.nlm.nih.gov/pubmed/31949910 http://dx.doi.org/10.1107/S2052252519016142

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