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Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases
Tannerella forsythia is an oral dysbiotic periodontopathogen involved in severe human periodontal disease. As part of its virulence factor armamentarium, at the site of colonization it secretes mirolysin, a metallopeptidase of the unicellular pappalysin family, as a zymogen that is proteolytically a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949598/ https://www.ncbi.nlm.nih.gov/pubmed/31949901 http://dx.doi.org/10.1107/S2052252519013848 |