Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling

BACKGROUND: Diabetic retinopathy (DR) is a serious microvascular complication of diabetes. This study demonstrates the antiangiogenic effects of scutellarin (SCU) on high glucose- and hypoxia-stimulated human retinal endothelial cells (HRECs) and on a diabetic rat model by oral administration. The a...

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Detalles Bibliográficos
Autores principales: Long, Lingli, Li, Yubin, Yu, Shuang, Li, Xiang, Hu, Yue, Long, Tengfei, Wang, Liqin, Li, Wenwen, Ye, Xiaoxin, Ke, Zunfu, Xiao, Haipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949683/
https://www.ncbi.nlm.nih.gov/pubmed/31976335
http://dx.doi.org/10.1155/2019/4875421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949683/
https://www.ncbi.nlm.nih.gov/pubmed/31976335
http://dx.doi.org/10.1155/2019/4875421

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