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Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling
BACKGROUND: Diabetic retinopathy (DR) is a serious microvascular complication of diabetes. This study demonstrates the antiangiogenic effects of scutellarin (SCU) on high glucose- and hypoxia-stimulated human retinal endothelial cells (HRECs) and on a diabetic rat model by oral administration. The a...
Autores principales: | Long, Lingli, Li, Yubin, Yu, Shuang, Li, Xiang, Hu, Yue, Long, Tengfei, Wang, Liqin, Li, Wenwen, Ye, Xiaoxin, Ke, Zunfu, Xiao, Haipeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949683/ https://www.ncbi.nlm.nih.gov/pubmed/31976335 http://dx.doi.org/10.1155/2019/4875421 |
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