The Coumarin Derivative 5′-Hydroxy Auraptene Suppresses Osteoclast Differentiation via Inhibiting MAPK and c-Fos/NFATc1 Pathways

The phytochemical substances, coumarin derivatives, have demonstrated antiresorptive bone effects by suppressing osteoclast differentiation in vitro and in vivo. Recently, we have identified 5′-hydroxy auraptene (5′-HA), a coumarin derivative isolated from Lotus lalambensis Schweinf, as a novel stim...

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Detalles Bibliográficos
Autores principales: Abdallah, Basem M., Ali, Enas M., Elsawy, Hany, Badr, Gehan M., Abdel-Moneim, Ashraf M., Alzahrani, Abdullah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949687/
https://www.ncbi.nlm.nih.gov/pubmed/31976330
http://dx.doi.org/10.1155/2019/9395146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949687/
https://www.ncbi.nlm.nih.gov/pubmed/31976330
http://dx.doi.org/10.1155/2019/9395146

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