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Nuclear Transit and HIV LTR Binding of NF-κB Subunits Held by IκB Proteins: Implications for HIV-1 Activation

No effective therapy to eliminate the HIV latently infected cell reservoir has been developed. One approach, “shock and kill”, employs agents that activate HIV, subsequently killing the activated infected cells and/or virus. Shock and kill requires agents that safely and effectively activate HIV. On...

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Detalles Bibliográficos
Autores principales: Khan, Sohrab Z., Gasperino, Sofia, Zeichner, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949894/
https://www.ncbi.nlm.nih.gov/pubmed/31888181
http://dx.doi.org/10.3390/v11121162