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Qualitative Assay to Detect Dopamine Release by Ligand Action on Nicotinic Acetylcholine Receptors

A pheochromocytoma of the rat adrenal medulla derived (a.k.a. PC12) cell-based assay for dopamine measurement by luminescence detection was customized for the qualitative evaluation of agonists and antagonists of nicotinic acetylcholine receptors (nAChRs). The assay mechanism begins with ligand bind...

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Detalles Bibliográficos
Autores principales: Marquart, Leanna A., Turner, Matthew W., McDougal, Owen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949981/
https://www.ncbi.nlm.nih.gov/pubmed/31757080
http://dx.doi.org/10.3390/toxins11120682