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Crotoxin Conjugated to SBA-15 Nanostructured Mesoporous Silica Induces Long-Last Analgesic Effect in the Neuropathic Pain Model in Mice

Neuropathic pain is a disease caused by structural and functional plasticity in central and peripheral sensory pathways that produce alterations in nociceptive processing. Currently, pharmacological treatment for this condition remains a challenge. Crotoxin (CTX), the main neurotoxin of Crotalus dur...

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Detalles Bibliográficos
Autores principales: Sant’Anna, Morena Brazil, Lopes, Flavia Souza Ribeiro, Kimura, Louise Faggionato, Giardini, Aline Carolina, Sant’Anna, Osvaldo Augusto, Picolo, Gisele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949982/
https://www.ncbi.nlm.nih.gov/pubmed/31757011
http://dx.doi.org/10.3390/toxins11120679