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Tangential Flow Filtration for the Concentration of Oncolytic Measles Virus: The Influence of Filter Properties and the Cell Culture Medium

The therapeutic use of oncolytic measles virus (MV) for cancer treatment requires >10(8) infectious MV particles per dose in a highly pure form. The concentration/purification of viruses is typically achieved by tangential flow filtration (TFF) but the efficiency of this process for the preparati...

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Detalles Bibliográficos
Autores principales: Loewe, Daniel, Grein, Tanja A., Dieken, Hauke, Weidner, Tobias, Salzig, Denise, Czermak, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950090/
https://www.ncbi.nlm.nih.gov/pubmed/31795406
http://dx.doi.org/10.3390/membranes9120160