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Tangential Flow Filtration for the Concentration of Oncolytic Measles Virus: The Influence of Filter Properties and the Cell Culture Medium
The therapeutic use of oncolytic measles virus (MV) for cancer treatment requires >10(8) infectious MV particles per dose in a highly pure form. The concentration/purification of viruses is typically achieved by tangential flow filtration (TFF) but the efficiency of this process for the preparati...
Autores principales: | Loewe, Daniel, Grein, Tanja A., Dieken, Hauke, Weidner, Tobias, Salzig, Denise, Czermak, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950090/ https://www.ncbi.nlm.nih.gov/pubmed/31795406 http://dx.doi.org/10.3390/membranes9120160 |
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