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Plasma Homocysteine and Polymorphisms of Genes Involved in Folate Metabolism Correlate with DNMT1 Gene Methylation Levels

DNA methyltransferase 1 (DNMT1) is responsible for the maintenance of DNA methylation patterns during cell division. Several human diseases are characterized by impaired DNMT1 gene methylation, but less is known about the factors that regulate DNMT1 promoter methylation levels. Dietary folates and r...

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Detalles Bibliográficos
Autores principales: Coppedè, Fabio, Stoccoro, Andrea, Tannorella, Pierpaola, Migliore, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950100/
https://www.ncbi.nlm.nih.gov/pubmed/31817852
http://dx.doi.org/10.3390/metabo9120298