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Genome Mining of Marine-Derived Streptomyces sp. SCSIO 40010 Leads to Cytotoxic New Polycyclic Tetramate Macrolactams

Polycyclic tetramate macrolactams (PTMs) biosynthetic gene cluster are widely distributed in different bacterial types, especially in Streptomyces species. The mining of the genomic data of marine-derived Streptomyces sp. SCSIO 40010 reveals the presence of a putative PTM-encoding biosynthetic gene...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhang, Wenjun, Jin, Hongbo, Zhang, Qingbo, Chen, Yuchan, Jiang, Xiaodong, Zhang, Guangtao, Zhang, Liping, Zhang, Weimin, She, Zhigang, Zhang, Changsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950151/
https://www.ncbi.nlm.nih.gov/pubmed/31775228
http://dx.doi.org/10.3390/md17120663