Single Spheroid Metabolomics: Optimizing Sample Preparation of Three-Dimensional Multicellular Tumor Spheroids

Tumor spheroids are important model systems due to the capability of capturing in vivo tumor complexity. In this work, the experimental design of metabolomics workflows using three-dimensional multicellular tumor spheroid (3D MTS) models is addressed. Non-scaffold based cultures of the HCT116 colon...

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Detalles Bibliográficos
Autores principales: Rusz, Mate, Rampler, Evelyn, Keppler, Bernhard K., Jakupec, Michael A., Koellensperger, Gunda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950217/
https://www.ncbi.nlm.nih.gov/pubmed/31847430
http://dx.doi.org/10.3390/metabo9120304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950217/
https://www.ncbi.nlm.nih.gov/pubmed/31847430
http://dx.doi.org/10.3390/metabo9120304

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