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Selection of preclinical models to evaluate intranasal brain cooling for acute ischemic stroke

Stroke accounts for a large proportion of global mortality and morbidity. Selective hypothermia, via intranasal cooling devices, is a promising intervention in acute ischemic stroke. However, prior to large clinical trials, preclinical studies in large animal models of ischemic stroke are needed to...

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Detalles Bibliográficos
Autores principales: Chen, Yining, Quddusi, Ayesha, Harrison, Kathleen A., Ryan, Paige E., Cook, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950506/
https://www.ncbi.nlm.nih.gov/pubmed/31950091
http://dx.doi.org/10.4103/bc.bc_20_19