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Cofilin-actin rod formation in experimental stroke is attenuated by therapeutic hypothermia and overexpression of the inducible 70 kD inducible heat shock protein (Hsp70)

BACKGROUND AND PURPOSE: Cofilin-actin rods are covalently linked aggregates of cofilin-1 and actin. Under ischemic conditions, these rods have been observed in neuronal dendrites and axons and may contribute to the loss of these processes. Hypothermia (Hypo) and the 70 kD inducible heat shock protei...

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Detalles Bibliográficos
Autores principales: Kurisu, Kota, You, Jesung, Zheng, Zhen, Won, Seok Joon, Swanson, Raymond A, Yenari, Midori A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950512/
https://www.ncbi.nlm.nih.gov/pubmed/31950099
http://dx.doi.org/10.4103/bc.bc_52_19