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Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians

Alu hypomethylation promotes genomic instability and is associated with aging and age-related diseases. Dietary factors affect global DNA methylation, leading to changes in genomic stability and gene expression with an impact on longevity and the risk of disease. This preliminary study aims to inves...

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Detalles Bibliográficos
Autores principales: Giacconi, Robertina, Malavolta, Marco, Bürkle, Alexander, Moreno-Villanueva, María, Franceschi, Claudio, Capri, Miriam, Slagboom, P. Eline, Jansen, Eugène H. J. M., Dollé, Martijn E. T., Grune, Tilman, Weber, Daniela, Hervonen, Antti, Stuetz, Wolfgang, Breusing, Nicolle, Ciccarone, Fabio, Zampieri, Michele, Aversano, Valentina, Caiafa, Paola, Formentini, Laura, Piacenza, Francesco, Pierpaoli, Elisa, Basso, Andrea, Provinciali, Mauro, Cardelli, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950565/
https://www.ncbi.nlm.nih.gov/pubmed/31817660
http://dx.doi.org/10.3390/nu11122986