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Fucoxanthin Alleviates Oxidative Stress through Akt/Sirt1/FoxO3α Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs

As one of the main marine carotenoids, fucoxanthin has strong antioxidant activity. FoxO3α, a member of the forkhead box O family of transcription factors, plays an important role in DN by regulating oxidative stress. The activity of FoxO3α is related to its phosphorylation and acetylation status, r...

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Detalles Bibliográficos
Autores principales: Yang, Guanyu, Jin, Lin, Zheng, Dongxiao, Tang, Xiaoliang, Yang, Junwei, Fan, Lingxuan, Xie, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950607/
https://www.ncbi.nlm.nih.gov/pubmed/31842414
http://dx.doi.org/10.3390/md17120702