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Fucoxanthin Alleviates Oxidative Stress through Akt/Sirt1/FoxO3α Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs
As one of the main marine carotenoids, fucoxanthin has strong antioxidant activity. FoxO3α, a member of the forkhead box O family of transcription factors, plays an important role in DN by regulating oxidative stress. The activity of FoxO3α is related to its phosphorylation and acetylation status, r...
Autores principales: | Yang, Guanyu, Jin, Lin, Zheng, Dongxiao, Tang, Xiaoliang, Yang, Junwei, Fan, Lingxuan, Xie, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950607/ https://www.ncbi.nlm.nih.gov/pubmed/31842414 http://dx.doi.org/10.3390/md17120702 |
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