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ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile

Adhesion G Protein-Coupled Receptor L4 (ADGRL4/ELTD1) is an endothelial cell adhesion G protein-coupled receptor (aGPCR) which regulates physiological and tumour angiogenesis, providing an attractive target for anti-cancer therapeutics. To date, ADGRL4/ELTD1′s full role and mechanism of function wit...

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Detalles Bibliográficos
Autores principales: Favara, David M., Zois, Christos E., Haider, Syed, Pires, Elisabete, Sheldon, Helen, McCullagh, James, Banham, Alison H., Harris, Adrian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950702/
https://www.ncbi.nlm.nih.gov/pubmed/31775252
http://dx.doi.org/10.3390/metabo9120287