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The Cellular Localization of the p42 and p46 Oligoadenylate Synthetase 1 Isoforms and Their Impact on Mitochondrial Respiration

The importance of the IFN-induced oligoadenylate synthetase (OAS) proteins and the OAS/RNase L pathway in the innate response against viral pathogens is well-established, however the observed differences in anti-viral activity between the human OAS1 p46 and p42 isoforms are not fully understood. The...

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Detalles Bibliográficos
Autores principales: Skrivergaard, Stig, Jensen, Monica Skou, Rolander, Tine Breckling, Nguyen, Tram Bao Ngoc, Bundgaard, Amanda, Nejsum, Lene N., Martensen, Pia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950736/
https://www.ncbi.nlm.nih.gov/pubmed/31817188
http://dx.doi.org/10.3390/v11121122