tRNA Dissociation from EF-Tu after GTP Hydrolysis: Primary Steps and Antibiotic Inhibition

In each round of ribosomal translation, the translational GTPase elongation factor Tu (EF-Tu) delivers a transfer RNA (tRNA) to the ribosome. After successful decoding, EF-Tu hydrolyzes GTP, which triggers a conformational change that ultimately results in the release of the tRNA from EF-Tu. To iden...

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Detalles Bibliográficos
Autores principales: Warias, Malte, Grubmüller, Helmut, Bock, Lars V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950810/
https://www.ncbi.nlm.nih.gov/pubmed/31711607
http://dx.doi.org/10.1016/j.bpj.2019.10.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950810/
https://www.ncbi.nlm.nih.gov/pubmed/31711607
http://dx.doi.org/10.1016/j.bpj.2019.10.028

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