Metformin alleviates muscle wasting post-thermal injury by increasing Pax7-positive muscle progenitor cells

BACKGROUND: Profound skeletal muscle wasting and weakness is common after severe burn and persists for years after injury contributing to morbidity and mortality of burn patients. Currently, no ideal treatment exists to inhibit muscle catabolism. Metformin is an anti-diabetic agent that manages hype...

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Detalles Bibliográficos
Autores principales: Yousuf, Yusef, Datu, Andrea, Barnes, Ben, Amini-Nik, Saeid, Jeschke, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950874/
https://www.ncbi.nlm.nih.gov/pubmed/31915055
http://dx.doi.org/10.1186/s13287-019-1480-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950874/
https://www.ncbi.nlm.nih.gov/pubmed/31915055
http://dx.doi.org/10.1186/s13287-019-1480-x

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