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Metformin alleviates muscle wasting post-thermal injury by increasing Pax7-positive muscle progenitor cells
BACKGROUND: Profound skeletal muscle wasting and weakness is common after severe burn and persists for years after injury contributing to morbidity and mortality of burn patients. Currently, no ideal treatment exists to inhibit muscle catabolism. Metformin is an anti-diabetic agent that manages hype...
Autores principales: | Yousuf, Yusef, Datu, Andrea, Barnes, Ben, Amini-Nik, Saeid, Jeschke, Marc G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950874/ https://www.ncbi.nlm.nih.gov/pubmed/31915055 http://dx.doi.org/10.1186/s13287-019-1480-x |
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