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Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia
BACKGROUND: Alzheimer’s disease is associated with the accumulation of intracellular Tau tangles within neurons and extracellular amyloid-β plaques in the brain parenchyma, which altogether results in synaptic loss and neurodegeneration. Extracellular concentrations of oligomers and aggregated prote...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950897/ https://www.ncbi.nlm.nih.gov/pubmed/31915009 http://dx.doi.org/10.1186/s12974-019-1694-y |