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Effect of β-cyclodextrin encapsulation on cytotoxic activity of acetylshikonin against HCT-116 and MDA-MB-231 cancer cell lines

Acetylshikonin (AcSh), as a red colored pigment found in roots of the plants from family Boraginaceae, showed excellent cytotoxic activity. Due to its hydrophobic nature, and thus poor bioavailability, the aim of this study was to prepare acetylshikonin/β-cyclodextrin (AcSh/β-CD) inclusion complex b...

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Detalles Bibliográficos
Autores principales: Vukic, Milena D., Vukovic, Nenad L., Popovic, Suzana Lj., Todorovic, Danijela V., Djurdjevic, Predrag M., Matic, Sanja D., Mitrovic, Marina M., Popovic, Ana M., Kacaniova, Miroslava M., Baskic, Dejan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950963/
https://www.ncbi.nlm.nih.gov/pubmed/31920439
http://dx.doi.org/10.1016/j.jsps.2019.11.015