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Effect of β-cyclodextrin encapsulation on cytotoxic activity of acetylshikonin against HCT-116 and MDA-MB-231 cancer cell lines
Acetylshikonin (AcSh), as a red colored pigment found in roots of the plants from family Boraginaceae, showed excellent cytotoxic activity. Due to its hydrophobic nature, and thus poor bioavailability, the aim of this study was to prepare acetylshikonin/β-cyclodextrin (AcSh/β-CD) inclusion complex b...
Autores principales: | Vukic, Milena D., Vukovic, Nenad L., Popovic, Suzana Lj., Todorovic, Danijela V., Djurdjevic, Predrag M., Matic, Sanja D., Mitrovic, Marina M., Popovic, Ana M., Kacaniova, Miroslava M., Baskic, Dejan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950963/ https://www.ncbi.nlm.nih.gov/pubmed/31920439 http://dx.doi.org/10.1016/j.jsps.2019.11.015 |
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