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Neuropeptide S-initiated sequential cascade mediated by OX(1), NK(1), mGlu(5) and CB(1) receptors: a pivotal role in stress-induced analgesia

BACKGROUND: Stress-induced analgesia (SIA) is an evolutionarily conserved phenomenon during stress. Neuropeptide S (NPS), orexins, substance P, glutamate and endocannabinoids are known to be involved in stress and/or SIA, however their causal links remain unclear. Here, we reveal an unprecedented se...

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Detalles Bibliográficos
Autores principales: Lee, Ming Tatt, Chiu, Yu-Ting, Chiu, Yu-Chun, Hor, Chia Chun, Lee, Hsin-Jung, Guerrini, Remo, Calo, Girolamo, Chiou, Lih-Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950992/
https://www.ncbi.nlm.nih.gov/pubmed/31915019
http://dx.doi.org/10.1186/s12929-019-0590-1