SOD2 ameliorates pulmonary hypertension in a murine model of sleep apnea via suppressing expression of NLRP3 in CD11b(+) cells

BACKGROUND: High prevalence of obstructive sleep apnea (OSA) in the pulmonary hypertension (PH) population suggests that chronic intermittent hypoxia (CIH) is an important pathogenic factor of PH. However, the exact mechanism of CIH induced PH is not clear. One of the molecules that plays a key role...

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Detalles Bibliográficos
Autores principales: Fu, Cuiping, Hao, Shengyu, Liu, Zilong, Xie, Liang, Wu, Xu, Wu, Xiaodan, Li, Shanqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951024/
https://www.ncbi.nlm.nih.gov/pubmed/31915037
http://dx.doi.org/10.1186/s12931-019-1270-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951024/
https://www.ncbi.nlm.nih.gov/pubmed/31915037
http://dx.doi.org/10.1186/s12931-019-1270-0

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