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SOD2 ameliorates pulmonary hypertension in a murine model of sleep apnea via suppressing expression of NLRP3 in CD11b(+) cells
BACKGROUND: High prevalence of obstructive sleep apnea (OSA) in the pulmonary hypertension (PH) population suggests that chronic intermittent hypoxia (CIH) is an important pathogenic factor of PH. However, the exact mechanism of CIH induced PH is not clear. One of the molecules that plays a key role...
Autores principales: | Fu, Cuiping, Hao, Shengyu, Liu, Zilong, Xie, Liang, Wu, Xu, Wu, Xiaodan, Li, Shanqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951024/ https://www.ncbi.nlm.nih.gov/pubmed/31915037 http://dx.doi.org/10.1186/s12931-019-1270-0 |
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