FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression

Pancreatic endocrine cell development into differentiated α- and β-cells is highly regulated and involves multiple transcription factors. However, the mechanisms behind the determination of α- and β-cell masses remains unclear. We previously identified Foxo1 CoRepressor (FCoR), which inhibits Foxo1...

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Detalles Bibliográficos
Autores principales: Kodani, Noriko, Nakae, Jun, Kobayashi, Masaki, Kikuchi, Osamu, Kitamura, Tadahiro, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951314/
https://www.ncbi.nlm.nih.gov/pubmed/31923647
http://dx.doi.org/10.1016/j.isci.2019.100798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951314/
https://www.ncbi.nlm.nih.gov/pubmed/31923647
http://dx.doi.org/10.1016/j.isci.2019.100798

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