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FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression
Pancreatic endocrine cell development into differentiated α- and β-cells is highly regulated and involves multiple transcription factors. However, the mechanisms behind the determination of α- and β-cell masses remains unclear. We previously identified Foxo1 CoRepressor (FCoR), which inhibits Foxo1...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951314/ https://www.ncbi.nlm.nih.gov/pubmed/31923647 http://dx.doi.org/10.1016/j.isci.2019.100798 |