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Genistein Inhibits Proliferation of BRCA1 Mutated Breast Cancer Cells: The GPR30-Akt Axis as a Potential Target

BACKGROUND: BRCA1 mutated breast cancer cells exhibit the elevated cell proliferation and the higher metastatic potential. G protein-coupled receptor 30 (GPR30) has been shown to regulate growth of hormonally responsive cancers, such as ovarian and breast cancers, and high expression of GPR30 is fou...

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Detalles Bibliográficos
Autores principales: Kim, Ga Yun, Suh, Jinyoung, Jang, Jeong-Hoon, Kim, Do-Hee, Park, Ock Jin, Park, Sue K., Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951321/
https://www.ncbi.nlm.nih.gov/pubmed/31950019
http://dx.doi.org/10.15430/JCP.2019.24.4.197