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The Prognostic Significance of TET2 Single Nucleotide Polymorphism in Egyptian Chronic Myeloid Leukemia

BACKGROUND: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm where pathogenesis is based on the oncoprotein termed BCR-ABL1.1 TET2 initiates DNA demethylation and is frequently mutated in hematological malignancies, including CML. The relation between TET2 acquisition and CML transfor...

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Detalles Bibliográficos
Autores principales: Hamed, Nahla A., Elhalawani, Nabil A., Kassem, Heba S., Ayad, Mona W., Dammag, Enas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951353/
https://www.ncbi.nlm.nih.gov/pubmed/31934314
http://dx.doi.org/10.4084/MJHID.2020.004