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Pharmacokinetics and enterohepatic circulation of jervine, an antitumor steroidal alkaloid from Veratrum nigrum in rats

Jervine, a novel steroidal alkaloid from Veratrum nigrum L., exhibits both antitumor effect and potential toxicity. The aim of study was to characterize the pharmacokinetic behaviors and enterohepatic circulation of jervine in rats. A rapid and simple ultra-high performance liquid chromatography-tan...

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Detalles Bibliográficos
Autores principales: Zheng, Bingjing, Wang, Caihong, Song, Wenwen, Ye, Xiaoxia, Xiang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951481/
https://www.ncbi.nlm.nih.gov/pubmed/31929946
http://dx.doi.org/10.1016/j.jpha.2019.04.004