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Imaging of singlet oxygen feedback delayed fluorescence and lysosome permeabilization in tumor in vivo during photodynamic therapy with aluminum phthalocyanine

Significance: Singlet oxygen is a key cytotoxic agent in photodynamic therapy (PDT). As such, its imaging is highly desirable, but existing direct imaging methods are still limited by the exceptionally low yield of the luminescence signal. Singlet oxygen feedback delayed fluorescence (SOFDF) of the...

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Detalles Bibliográficos
Autores principales: Scholz, Marek, Gunn, Jason R., Luke, Geoffrey P., Pogue, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951482/
https://www.ncbi.nlm.nih.gov/pubmed/31920049
http://dx.doi.org/10.1117/1.JBO.25.6.063806