Irbesartan desmotropes: Solid-state characterization, thermodynamic study and dissolution properties

Irbesartan (IBS) is a tetrazole derivative and antihypertensive drug that has two interconvertible structures, 1H- and 2H-tautomers. The difference between them lies in the protonation of the tetrazole ring. In the solid-state, both tautomers can be isolated as crystal forms A (1H-tautomer) and B (2...

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Detalles Bibliográficos
Autores principales: Araya-Sibaja, Andrea Mariela, Maduro de Campos, Carlos Eduardo, Fandaruff, Cinira, Vega-Baudrit, José Roberto, Guillén-Girón, Teodolito, Navarro-Hoyos, Mirtha, Cuffini, Silvia Lucía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951487/
https://www.ncbi.nlm.nih.gov/pubmed/31929943
http://dx.doi.org/10.1016/j.jpha.2019.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951487/
https://www.ncbi.nlm.nih.gov/pubmed/31929943
http://dx.doi.org/10.1016/j.jpha.2019.07.001

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