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Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer
Endothelin-1 (ET-1) and its two receptors, endothelin receptor A (ET(A)R) and endothelin receptor B (ET(B)R) exhibit deregulated overexprerssion in pancreatic ductal adenocarcinoma (PDAC) and pancreatitis. We examined the expression pattern of endothelin (ET) axis components in the murine models of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951489/ https://www.ncbi.nlm.nih.gov/pubmed/31923844 http://dx.doi.org/10.1016/j.neo.2019.11.001 |