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Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer

Endothelin-1 (ET-1) and its two receptors, endothelin receptor A (ET(A)R) and endothelin receptor B (ET(B)R) exhibit deregulated overexprerssion in pancreatic ductal adenocarcinoma (PDAC) and pancreatitis. We examined the expression pattern of endothelin (ET) axis components in the murine models of...

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Detalles Bibliográficos
Autores principales:	Gupta, Suprit, Prajapati, Avi, Gulati, Mansi, Gautam, Shailendra K., Kumar, Sushil, Dalal, Vipin, Talmon, Geoffrey A., Rachagani, Satyanarayana, Jain, Maneesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951489/ https://www.ncbi.nlm.nih.gov/pubmed/31923844 http://dx.doi.org/10.1016/j.neo.2019.11.001

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