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Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro

Variation in methotrexate (MTX) efficacy represents a significant barrier to early and effective disease control in the treatment of autoimmune arthritis. We hypothesize that the utilization of metabolomic techniques will allow for an improved understanding of the biochemical basis for the pharmacol...

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Detalles Bibliográficos
Autores principales: Funk, Ryan S., Singh, Rakesh K., Becker, Mara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951846/
https://www.ncbi.nlm.nih.gov/pubmed/31651077
http://dx.doi.org/10.1111/cts.12694