Variability in In Vitro OATP1B1/1B3 Inhibition Data: Impact of Incubation Conditions on Variability and Subsequent Drug Interaction Predictions

As the research into the organic anion transporting polypeptides (OATPs) continues to grow, it is important to ensure that the data generated are accurate and reproducible. In the in vitro evaluation of OATP1B1/1B3 inhibition, there are many variables that can contribute to variability in the result...

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Detalles Bibliográficos
Autores principales: McFeely, Savannah J., Ritchie, Tasha K., Ragueneau‐Majlessi, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951852/
https://www.ncbi.nlm.nih.gov/pubmed/31468718
http://dx.doi.org/10.1111/cts.12691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951852/
https://www.ncbi.nlm.nih.gov/pubmed/31468718
http://dx.doi.org/10.1111/cts.12691

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