Comparing Model Performance in Characterizing the PK/PD of the Anti‐Myostatin Antibody Domagrozumab

Modeling and simulation provides quantitative information on target coverage for dose selection. Optimal model selection often relies on fit criteria and is not necessarily mechanistically driven. One such case is discussed where healthy volunteer data of an anti‐myostatin monoclonal antibody domagr...

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Detalles Bibliográficos
Autores principales: Tiwari, Abhinav, Bhattacharya, Indranil, Chan, Phylinda L.S., Harnisch, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951913/
https://www.ncbi.nlm.nih.gov/pubmed/31550073
http://dx.doi.org/10.1111/cts.12693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951913/
https://www.ncbi.nlm.nih.gov/pubmed/31550073
http://dx.doi.org/10.1111/cts.12693

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