Soluble AXL as a marker of disease progression and survival in melanoma

Receptor tyrosine kinase AXL is a one-pass transmembrane protein upregulated in cancers and associated with lower survival and therapy resistance. AXL can be cleaved by the A Disintegrin and Metalloproteinases (ADAM)10 and ADAM17, yielding a soluble version of the protein. Elevated soluble AXL (sAXL...

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Detalles Bibliográficos
Autores principales: Flem-Karlsen, Karine, Nyakas, Marta, Farstad, Inger Nina, McFadden, Erin, Wernhoff, Patrik, Jacobsen, Kari Dolven, Flørenes, Vivi Ann, Mælandsmo, Gunhild Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952099/
https://www.ncbi.nlm.nih.gov/pubmed/31917795
http://dx.doi.org/10.1371/journal.pone.0227187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952099/
https://www.ncbi.nlm.nih.gov/pubmed/31917795
http://dx.doi.org/10.1371/journal.pone.0227187

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