Leveraging allelic imbalance to refine fine-mapping for eQTL studies

Many disease risk loci identified in genome-wide association studies are present in non-coding regions of the genome. Previous studies have found enrichment of expression quantitative trait loci (eQTLs) in disease risk loci, indicating that identifying causal variants for gene expression is importan...

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Detalles Bibliográficos
Autores principales: Zou, Jennifer, Hormozdiari, Farhad, Jew, Brandon, Castel, Stephane E., Lappalainen, Tuuli, Ernst, Jason, Sul, Jae Hoon, Eskin, Eleazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952111/
https://www.ncbi.nlm.nih.gov/pubmed/31834882
http://dx.doi.org/10.1371/journal.pgen.1008481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952111/
https://www.ncbi.nlm.nih.gov/pubmed/31834882
http://dx.doi.org/10.1371/journal.pgen.1008481

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