The effect of mutations derived from mouse-adapted H3N2 seasonal influenza A virus to pathogenicity and host adaptation

Elucidating the genetic basis of influenza A viruses (IAVs) is important to understand which mutations will determine the virulence and the host range of mammals. Here, seasonal H3N2 influenza was adapted in mice by serial passage and four mutants, each carrying amino acid substitutions related to m...

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Detalles Bibliográficos
Autores principales: Choi, Eun-Ji, Lee, Young Jae, Lee, Jin-Moo, Kim, Yeon-Jung, Choi, Jang-Hoon, Ahn, Byeongwoo, Kim, Kisoon, Han, Myung Guk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952113/
https://www.ncbi.nlm.nih.gov/pubmed/31917822
http://dx.doi.org/10.1371/journal.pone.0227516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952113/
https://www.ncbi.nlm.nih.gov/pubmed/31917822
http://dx.doi.org/10.1371/journal.pone.0227516

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