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Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC β-Lactamases from Klebsiella pneumoniae Clinical Isolates

Carbapenemases confer resistance to nearly all β-lactam antibiotics. The extensive spread of carbapenemase-producing multidrug-resistant bacteria contributes significantly to hospital-acquired infections. We have developed a novel protein-based binding assay that identifies KPC β-lactamases from cli...

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Detalles Bibliográficos
Autores principales: Lu, Shuo, Soeung, Victoria, Nguyen, Hoang A. T., Long, S. Wesley, Musser, James M., Palzkill, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952207/
https://www.ncbi.nlm.nih.gov/pubmed/31915233
http://dx.doi.org/10.1128/mSphere.00918-19