Cargando…

Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC β-Lactamases from Klebsiella pneumoniae Clinical Isolates

Carbapenemases confer resistance to nearly all β-lactam antibiotics. The extensive spread of carbapenemase-producing multidrug-resistant bacteria contributes significantly to hospital-acquired infections. We have developed a novel protein-based binding assay that identifies KPC β-lactamases from cli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Shuo, Soeung, Victoria, Nguyen, Hoang A. T., Long, S. Wesley, Musser, James M., Palzkill, Timothy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952207/ https://www.ncbi.nlm.nih.gov/pubmed/31915233 http://dx.doi.org/10.1128/mSphere.00918-19

Ejemplares similares

Identification of Klebsiella pneumoniae that produces β-Lactamase bla(KPC )gene
por: Sá Queiroz, Julio Henrique Ferreira de, et al.
Publicado: (2014)

Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases
por: Palzkill, Timothy
Publicado: (2018)

Worldwide Diversity of Klebsiella pneumoniae That Produce β-Lactamase bla(KPC-2) Gene
por: Cuzon, Gaëlle, et al.
Publicado: (2010)

Distribution of β-Lactamase Genes and Genetic Context of bla(KPC-2) in Clinical Carbapenemase-Producing Klebsiella pneumoniae Isolates
por: Liu, Hongmao, et al.
Publicado: (2021)

Prevalence of blaKPC and its occurrence with other beta-lactamases in Klebsiella pneumoniae
por: Remya, Poothakuzhiyil, et al.
Publicado: (2018)

KPC-2 β-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate
por: Mehta, Shrenik C., et al.
Publicado: (2020)

Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study
por: Krishnan, Nikhil P., et al.
Publicado: (2015)

Genomic Characterization of KPC-31 and OXA-181 Klebsiella pneumoniae Resistant to New Generation of β-Lactam/β-Lactamase Inhibitor Combinations
por: Muresu, Narcisa, et al.
Publicado: (2022)

Emergence of New Delhi Metallo-Beta-Lactamase (NDM) and Klebsiella pneumoniae Carbapenemase (KPC) Production by Escherichia coli and Klebsiella pneumoniae in Southern Vietnam and Appropriate Methods of Detection: A Cross-Sectional Study
por: Hoang, Cuong Q., et al.
Publicado: (2019)

Genomic analysis and antimicrobial activity of β-lactam/β-lactamase inhibitors and other agents against KPC-producing Klebsiella pneumoniae clinical isolates from Brazilian hospitals
por: Camargo, Carlos Henrique, et al.
Publicado: (2023)

Emergence of KPC-producing Klebsiella pneumoniae in Italy
por: Fontana, Carla, et al.
Publicado: (2010)

KPC Type β-Lactamase, Rural Pennsylvania
por: Pope, Jonathan, et al.
Publicado: (2006)

Prevalence of bla(KPC-2), bla(KPC-3) and bla(KPC-30)—Carrying Plasmids in Klebsiella pneumoniae Isolated in a Brazilian Hospital
por: Migliorini, Letícia B., et al.
Publicado: (2021)

Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 β-lactamase
por: Furey, Ian M., et al.
Publicado: (2021)

Emergence of Klebsiella pneumoniae clinical isolates producing KPC-2 carbapenemase in Cuba
por: Quiñones, D, et al.
Publicado: (2014)

AmpC β-lactamases in nosocomial isolates of Klebsiella pneumoniae from India
por: Gupta, Varsha, et al.
Publicado: (2012)

Prevalence of Extended Spectrum β-lactamase-Producing Klebsiella pneumoniae in Clinical Isolates
por: Ali Abdel Rahim, Khalid Abdalla, et al.
Publicado: (2014)

Alliance of Efflux Pumps with β-Lactamases in Multidrug-Resistant Klebsiella pneumoniae Isolates
por: Maurya, Navdezda, et al.
Publicado: (2019)

Rapid and sensitive detection of bla(KPC) gene in clinical isolates of Klebsiella pneumoniae by a molecular real-time assay
por: Mosca, Adriana, et al.
Publicado: (2013)

Management of infections due to KPC-producing Klebsiella pneumoniae
por: Deresinski, Stanley C, et al.
Publicado: (2009)

KPC-producing Klebsiella pneumoniae, finally targeting Turkey
por: Labarca, J, et al.
Publicado: (2014)

Resistance to ceftazidime-avibactam in a KPC-2–producing Klebsiella pneumoniae caused by the extended-spectrum beta-lactamase VEB-25
por: Findlay, Jacqueline, et al.
Publicado: (2023)

Studies on the Reactions of Biapenem with VIM Metallo β-Lactamases and the Serine β-Lactamase KPC-2
por: Lucic, Anka, et al.
Publicado: (2022)

The Effect of β-Lactam Antibiotics on the Evolution of Ceftazidime/Avibactam and Cefiderocol Resistance in KPC-Producing Klebsiella pneumoniae
por: Zhang, Ping, et al.
Publicado: (2023)

Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance
por: Chen, Luke F, et al.
Publicado: (2012)

Polymyxins and Doripenem Combination Against KPC-Producing Klebsiella pneumoniae
por: Lee, Grace C., et al.
Publicado: (2013)

First detection of KPC-3-producing Klebsiella pneumoniae in Albania
por: Kostyanev, T., et al.
Publicado: (2015)

The role of the bla(KPC) gene in antimicrobial resistance of Klebsiella pneumoniae
por: Ghasemnejad, Atossa, et al.
Publicado: (2019)

In vitro Optimization of Ceftazidime/Avibactam for KPC-Producing Klebsiella pneumoniae
por: Huang, Yanqin, et al.
Publicado: (2021)

The effect of Lactobacillus with prebiotics on KPC-2-producing Klebsiella pneumoniae
por: Tang, Hung-Jen, et al.
Publicado: (2022)

Isolation of a Klebsiella pneumoniae Isolate of Sequence Type 258 Producing KPC-2 Carbapenemase in Korea
por: Roh, Kyoung Ho, et al.
Publicado: (2011)

Isolation of a Ceftazidime-Avibactam-Resistant bla(KPC-71)-Positive Klebsiella pneumoniae Clinical Isolate
por: Shen, Siquan, et al.
Publicado: (2022)

Population Genomic Analysis of 1,777 Extended-Spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Isolates, Houston, Texas: Unexpected Abundance of Clonal Group 307
por: Long, S. Wesley, et al.
Publicado: (2017)

Molecular epidemiology of KPC-producing Klebsiella pneumoniae clinical isolates in hospitals in North-Western Tuscany
por: Buzzigoli, A, et al.
Publicado: (2011)

Two Distinct Genotypes of KPC-2-Producing Klebsiella pneumoniae Isolates from South Korea
por: Kim, Jee Hong, et al.
Publicado: (2021)

Isolation of the first IMP-4 metallo-β-lactamase producing Klebsiella pneumoniae in Tianjin, China
por: Li, Jing, et al.
Publicado: (2012)

Detection of β-Lactamases and Outer Membrane Porins among Klebsiella pneumoniae Strains Isolated in Iran
por: Hashemi, Ali, et al.
Publicado: (2014)

Diversity and Distribution of β-Lactamase Genes Circulating in Indian Isolates of Multidrug-Resistant Klebsiella pneumoniae
por: Shukla, Suraj, et al.
Publicado: (2023)

Prevalence of Extended-Spectrum β-Lactamases in Multidrug-Resistant Klebsiella pneumoniae Isolates in Jordanian Hospitals
por: Al-Sheboul, Suhaila A., et al.
Publicado: (2023)

Plasmid diversity among genetically related Klebsiella pneumoniae bla(KPC-2) and bla(KPC-3) isolates collected in the Dutch national surveillance
por: Hendrickx, Antoni P. A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f7ib5oc1rqf89ns7oc0jnp9fvs