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The effect of NAMPT deletion in projection neurons on the function and structure of neuromuscular junction (NMJ) in mice
Nicotinamide adenine dinucleotide (NAD(+)) plays a critical role in energy metabolism and bioenergetic homeostasis. Most NAD(+) in mammalian cells is synthesized via the NAD(+) salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme, converting nicotinamide...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952356/ https://www.ncbi.nlm.nih.gov/pubmed/31919382 http://dx.doi.org/10.1038/s41598-019-57085-4 |