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The effect of NAMPT deletion in projection neurons on the function and structure of neuromuscular junction (NMJ) in mice

Nicotinamide adenine dinucleotide (NAD(+)) plays a critical role in energy metabolism and bioenergetic homeostasis. Most NAD(+) in mammalian cells is synthesized via the NAD(+) salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme, converting nicotinamide...

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Detalles Bibliográficos
Autores principales: Lundt, Samuel, Zhang, Nannan, Wang, Xiaowan, Polo-Parada, Luis, Ding, Shinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952356/
https://www.ncbi.nlm.nih.gov/pubmed/31919382
http://dx.doi.org/10.1038/s41598-019-57085-4

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