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Melanoma cell-derived exosomes in plasma of melanoma patients suppress functions of immune effector cells

Melanoma patients’ plasma contains exosomes produced by malignant and normal cells. Plasma exosomes were isolated and separated by immunocapture into two fractions: melanoma cell-derived exosomes (MTEX) and normal cell-derived exosomes (non-MTEX). Immunosuppressive effects of MTEX on primary human i...

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Detalles Bibliográficos
Autores principales: Sharma, Priyanka, Diergaarde, Brenda, Ferrone, Soldano, Kirkwood, John M., Whiteside, Theresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952363/
https://www.ncbi.nlm.nih.gov/pubmed/31919420
http://dx.doi.org/10.1038/s41598-019-56542-4